CardaxEP Twin

Start with the CardaxEP template or use prepared imaging to fit atrial and ventricular anatomy. Chamber measurements provide another starting point when surfaces are unavailable.

• Fit the atria to prepared CT or MRI surfaces or estimate geometry from reported chamber volumes.
• Register the ventricular model against left and right ventricular surfaces and the epicardium.
• Rebuild conduction structures, fiber directions, and ECG lead fields on the fitted anatomy.

Inspect reported values before applying them to a model. The review shows what each selected value can change and reports differences that remain after the fit.

• Review chamber volumes, wall thickness, and other dimensions alongside the model.
• Review hemodynamic inputs such as pressure and cardiac output before fitting the circulation.
• Reopen saved research cases and compare fitted values with the original measurements.

Explore how the location and depth of modeled scar affect activation. Imaging and voltage maps provide different kinds of information and can inform different parts of the model.

• Use supported late gadolinium enhancement MRI inputs to place modeled dense scar and border zone.
• Explore CT wall thinning as a research proxy for scar where supported.
• Use imported electroanatomic voltage data to inform the endocardial substrate and inspect the resulting activation.

Follow a simulated beat from electrical activation to wall motion and hemodynamics. The circulation can be fitted after the chamber geometry is established.

• Visualize electrically driven contraction of the beating heart.
• Inspect simulated pressures, chamber volumes, and pressure-volume loops.
• Compare the model’s pressures, volumes, or output with the source measurements used in the fit.

Use the familiar CardaxEP laboratory on the fitted heart. Change one part of the model and watch how the rhythm or recording responds.

• Position virtual catheters and inspect intracardiac electrograms alongside the simulated 12-lead ECG.
• Use programmed stimulation, activation maps, and simulated ablation to explore possible mechanisms.
• Compare template anatomy with a fitted model to see where geometry and substrate change the result.

Run research experiments across synthetic cases. The virtual cohort tools let you vary the model systematically and keep simulated records distinct from clinical data.

• Vary chamber size, scar distribution, and circulation assumptions across modeled cases.
• Compare activation timing, ECG features, and modeled responses to stimulation.
• Rerun a synthetic case with one assumption changed to see which outputs are sensitive to it.

CardaxEP Twin is a research environment. A fitted model is an approximation, and a simulated arrhythmia is a result to investigate.

• Keep observed measurements, fitted values, and modeling assumptions distinct.
• Use fit residuals to identify measurements the model does not reproduce.
• Use the output for simulation research; it is not validated for diagnosis, treatment planning, or prediction of individual clinical outcomes.